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Jos Morales, MD, a vascular neurologist and neurointerventional surgeon at Providence Saint Johns Health Center in Santa Monica, CA, also not involved in this review, told MNT that microglias effect on the neurovascular unit has been associated with dementia. He suggested that: [GLP-1 drugs] could potentially modulate inflammation to reduce the propensity for developing dementias such as Alzheimers disease, particularly in the setting of metabolic syndrome. Morales also explained that in people who have glycemia or type 2 diabetes, the inflammation of the blood-brain barrier can lead to progressive damage to the brain over longer periods. He noted that trials that combine neuroimaging techniques that measure the blood-brain barrier and GLP-1 treatment are needed and could prove that these drugs have neuroprotective benefits.
Identification of genetic polymorphisms at the glutathione S -transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer
10.7150/thno.36120 Theranostics 102 LinS.LeeW
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Possible risk of pancreatitis and thyroid cancer: Although rare, these serious side effects have been observed in some patients
